TruBlue LASER
445 nm · ENT · A.R.C. since 1996

There's Blue.Then there's TruBlue.

For almost a decade, TruBlue has set the standard for precision laser surgery in ENT — the deepest clinical evidence base and the most complete product portfolio in the category.

First
in ENT blue laser
Most Evidenced
445 nm · peer-reviewed
Globally Trusted
surgeons worldwide
The Original Blue Laser in ENT

The platform that defined blue laser surgery.

When A.R.C. introduced TruBlue, it established an entirely new approach to laser surgery in ENT — for the first time, surgeons could harness the unique tissue interaction of blue laser energy on the most delicate structures of the voice, ear, and airway. Since then, blue laser has become an essential tool in modern ENT, and TruBlue remains the platform that defined the field — continuing to evolve with capabilities no other blue laser system can match, backed by decades of A.R.C. laser engineering.

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Wavelength
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Years A.R.C.
ENT Portfolio

Everything you need for every case, every time.

TruBlue is part of a comprehensive surgical laser portfolio designed to support ENT surgeons across multiple applications — integrating wavelengths, fibers, accessories, and compatible technologies that enable surgeons to treat a variety of conditions with a single, proven system.

ApplicationsLaryngologyOtologyRhinologyOffice-Based
Origin · Science

The origin of blue laser surgery in ENT.

Before TruBlue, ENT laser surgery had an unsolved problem: no single wavelength could cut precisely and coagulate effectively.

CO₂ excels at cutting but offers poor hemostasis. KTP achieves photoangiolysis, but cutting is limited — and the platform is no longer in production. The 445 nm wavelength proved both capabilities can coexist in a portable, fiber-delivered system.

The 445 nm wavelength sits at a peak of oxyhemoglobin absorption that exceeds both KTP (532 nm) and argon (514 nm), while remaining largely transparent to water. This photoangiolytic effect enables selective targeting of subepithelial vasculature while protecting the overlying epithelium.

Peer-Reviewed Findings/ 06 cited
  • Superior Tissue Selectivity

    High hemoglobin absorption with minimal thermal spread — reduces scarring risk and preserves the vibratory layer.

    Balouch, 2023
  • Reduced Scarring

    Significant fibrosis observed in vocal folds after KTP treatment; no such evidence in Wolf TruBlue cases.

    Lin, 2020
  • Visibility in a Drier Field

    The 445 nm absorption profile lets surgeons maintain visibility while controlling bleeding.

    González-Herranz, 2023
  • Minimal Collateral Damage

    Touch or near-touch technique for vascular lesions: effective coagulation with virtually no thermal effect on adjacent epithelium.

    Sataloff, 2021
  • Close and Clean Margins

    Vaporization of Tis, T1, and T2 glottic cancer tumors with close margins while preserving oncologic outcomes.

    Rosow, 2024
  • Dual Tissue Effect Confirmed

    Early laryngeal validation: 445 nm produces CO₂-like non-contact cutting with simultaneous photoangiolytic coagulation.

    Hess, 2018
Clinical Applications

Precision where it matters most.

TruBlue's unique tissue interaction properties make it a versatile tool across ENT subspecialties. Select an application to explore the clinical context, featured procedures, and supporting literature.

4.1

Laryngology

Laryngology presents some of the most technically demanding challenges in ENT surgery. TruBlue's 445 nm wavelength enables CO₂-like cutting accuracy with simultaneous coagulation — reducing bleeding while preserving adjacent epithelium. The photoangiolytic effect selectively targets subepithelial vasculature, making it particularly effective for vascular lesions of the larynx.

Key Procedures/ 10
  • Vocal fold lesions (papilloma, cysts, polyps, nodules)
  • T1/T2 glottic carcinoma resection
  • Arytenoid reduction
  • Supraglottoplasty (adult + pediatric)
  • Posterior laryngeal stenosis
  • Cordectomy
  • Oral cavity tumor resection
  • Subglottic stenosis treatment
  • Tracheal lesion management
  • Recurrent respiratory papillomatosis
Procedure Videos · Laryngology
/ 10
· Additional literature + detail pages available on request ·
Clinical Evidence Library

The most clinically established blue laser in ENT.

Peer-reviewed publications — spanning laryngology, otology, rhinology, phonosurgery, and general otorhinolaryngology. Filter by specialty, open a card to read the full abstract with DOI.

Publications
34
Specialties
5
Years
20182024
Sort
Full Library

Download the complete PDF brochure with all 34 abstracts, DOI links, and citation metadata. 7 years of 445 nm blue laser clinical experience in a single document.

Download Library PDF
A.R.C. Laser · 30 Years

Celebrating 30 years of laser innovation.

Since 1996, A.R.C. has developed precision tools for surgeons who operate in the most delicate anatomical environments — consistently partnering with clinicians to push what laser surgery can achieve.

1996
01 / 09

A.R.C. Laser founded

A.R.C. Laser GmbH established in Nürnberg, Germany.

.
02 / 09

First surgical laser platform

The first-generation surgical laser ships to customers.

.
03 / 09

Fiber-delivered ENT systems

Introduction of fiber-delivered laser systems purpose-built for ENT.

2017
04 / 09

445 nm TruBlue introduced

The first blue laser platform for ENT surgery goes to market.

.
05 / 09

First peer-reviewed validation

Hess et al. publishes the validating 445 nm study — laryngeal dual tissue effect confirmed.

.
06 / 09

FDA 510(k) clearance

TruBlue Wolf 445 cleared for incision, excision, vaporization, ablation, hemostasis, and coagulation of soft tissue.

2019
07 / 09

FlowControl introduced

Active CO₂ cooling + integrated smoke evacuation as a plug-and-play hardware add-on.

2026
08 / 09

30th Anniversary

Three decades of laser engineering in Nürnberg.

today
09 / 09

Wolf TruBlue Pro launched

The flagship: PentaPulse (5 emission modes) + FlowControl, standard.

← drag · scroll · swipe → · dates TBD to be confirmed with A.R.C.
Reference Users · Laryngology

Trusted by the surgeons who set the standard.

TruBlue is used by laryngologists across three regions — clinical collaborators and reference users who have shaped how blue laser surgery is practiced. Every entry below is a practicing physician, not a distributor.

Physicians
52
Cities
43
Countries
24
222252
Reference Users
52 Laryngology physicians
across all regions · alphabetical
  • Dr. Jean Abitbol
    Clinique BLOMET
    Paris · France
  • Prof. Krivopalov Aleksandr
    Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech
    St. Petersburg · Russia
  • Mohamed Hasan Abdulatif Ahmed Al Ali
    Sheikh Khalifa Medical City
    Abu Dhabi · UAE
  • Jennifer Anderson, MD, FRCSC
    St. Michael's Hospital
    Toronto · Canada
  • Bakotina Anna
    Moscow State University of Medicine and Dentistry · Clinical Center of Maxillofacial, Reconstructive and Recovery and Plastic Surgery
    Moscow · Russia
  • Xander van Bemmel, MD, PhD
    Medical Spectrum Twente
    Enschede · Netherlands
  • Prof. Dr. Christopher Bohr
    University Clinic Regensburg
    Regensburg · Germany
  • Kristian Bork, MD PhD
    Rigshospitalet
    Copenhagen · Denmark
  • Simon Brisebois, MD, MSc, FRCSC
    University of Sherbrooke Health Campus
    Sherbrooke · Canada
  • Guillermo Campos, MD
    Instituto de Laringología Asociación Médica de Bogotá
    Bogotá · Colombia
  • Dr. Seth Daily
    University of Wisconsin School of Medicine · Section of Laryngology and Voice Surgery
    Madison · USA
  • Tang Chi Ho Eric, MD, MBChB, MRCSEd, FRCS, FRCSEd, FHKCORL, FHKAM
    Chinese University of Hong Kong
    Hong Kong · Hong Kong
  • D.ssa Marta Filauro
    San Martino University Hospital
    Genoa · Italy
  • Dr. Ramone Franko
    Mass Eye & Ear Infirmary · Voice and Speech Laboratory · Harvard Medical School
    Boston · USA
  • Guzman Fugasot
    Hospital Británico and Hospital de Clínicas Universitario
    Montevideo · Uruguay
  • Adj. Prof. Ahmed Geneid, MD
    Helsinki University Hospital and Orton Voice Clinic
    Helsinki · Finland
  • Pr. Antoine Giovanni
    ENT Hospital la Conception
    Marseille · France
  • Yaniv Hamzany, MD
    Rabin Medical Center
    Petah Tikva · Israel
  • Anastasios G. Hantzakos, MD, PhD, MHA, FEBORL
    Cleveland Clinic Abu Dhabi
    Abu Dhabi · UAE
  • Dr. Georgina Harris, MBBS, BSc, FRACS
    The Voice Centre Australia · St Vincent's Hospital
    Sydney · Australia
  • Prof. Diab Hassan
    National Medical Research Center for Otorhinolaryngology
    Moscow · Russia
  • Dr. Victor Hernandez
    Clinica Colombia and Hospital Universitario Clinica San Rafael
    Bogotá · Colombia
  • Prof. Dr. Markus Hess
    Medical Voice Center
    Hamburg · Germany
  • Henry T. Hoffman, MD, MS, FACS
    University of Iowa Hospitals & Clinics
    Iowa City · USA
  • Michel van Horen, MD, PhD
    Pantein Medical Center
    Boxmeer · Netherlands
  • Andreas Jørkov, MD
    Zealand University Hospital Køge
    Køge · Denmark
  • Yakubu Karagama, MBBS, DLO, MSc, FRCS (ORL-HN), PGMed Cert
    Guy's and St Thomas Hospital
    London · United Kingdom
  • Prof. Dr. Andreas Knopf
    University Clinic Freiburg
    Freiburg · Germany
  • Yonatan Lahav, MD
    Kaplan Medical Center
    Rehovot · Israel
  • Budeykina Liliya
    City Clinical Hospital of the Department of Health of the City of Moscow
    Moscow · Russia
  • William L. Lim, MD, FPSOHNS
    St. Luke's Medical Center, Bonifacio GC
    Manila · Philippines
  • Emeritus Prof Hans Mahieu
    Ruysdael Clinics
    Amsterdam · Netherlands
  • Prof. Nersesyan Marina
    Patrice Lumumba People's Friendship University of Russia
    Moscow · Russia
  • Dr. Lance Maron
    Netcare Park Lane Hospital
    Johannesburg · South Africa
  • Kevin Smith MA (Cantab) MBBS MRCS
    DOHNS FRACS(OHNS) Auckland Head and Neck Specialists · Waitemata Health
    Auckland · New Zealand
  • Prof. Dr. Dirk Mürbe
    Charité · Clinic for Audiology and Phoniatrics
    Berlin · Germany
  • Daniel Novakovic, FRAC(OHNS), MBBS, MPH, BSc
    The University of Sydney · The Voice Centre Australia · St Vincent's Hospital
    Sydney · Australia
  • Prof. Giorgio Peretti
    San Martino University Hospital
    Genoa · Italy
  • Shamkina Polina
    Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech
    St. Petersburg · Russia
  • PhD Pavel Pryanikov
    Russian Children Clinical Hospital
    Moscow · Russia
  • Pr. Erwan De Mones Del Pujol
    ENT-CHU Bordeaux
    Bordeaux · France
  • David Edward Rossow, MD
    UHealth University of Miami Health System
    Miami · USA
  • Adam D. Rubin, MD
    Lakeshore Professional Voice Center · Lakeshore Ear, Nose & Throat Center
    Detroit · USA
  • Muhammad Arfiza Putra Saragih, MD
    ORL-HNS Haji Adam Malik General Hospital · North Sumatra
    Medan · Indonesia
  • Robert T. Sataloff, MD, DMA, FACS
    Drexel University College of Medicine
    Philadelphia · USA
  • Elisabeth Sjögren, MD PhD
    Leiden University Hospital
    Leiden · Netherlands
  • Jurjaan Snelleman, MD
    Meander Medical Center and Ruysdael Clinics
    Amersfoort · Netherlands
  • Prim. Univ.-Prof. Dr. Georg Sprinzl
    University Clinic St. Pölten
    St. Pölten · Austria
  • Prof. Dr. Holger Sudhoff
    Clinic Bielefeld
    Bielefeld · Germany
  • Monique Verguts, MD
    ORL-HNS Voice Clinic · European Institute of ORL-HNS GZA
    Antwerp · Belgium
  • As. MUDr. Michal Zabrodsky
    Motol University Hospital · Department of Otorhinolaryngology and Head & Neck Surgery
    Prague · Czech Republic
  • Fermin M. Zubiaur, MD, FACS
    Voice Clinic Mexico City
    Mexico City · Mexico
· Hover map or list to cross-highlight · Click to view doctor details · Data from A.R.C. Laser reference brochure 04/2024
Training · Education

Supporting the next generation of surgeons.

A.R.C. works closely with physicians and academic institutions to support education and training in laser-based ENT surgery — workshops, clinical collaborations, and programs that help surgeons use TruBlue effectively and safely.

Online
A.R.C. Academy

Clinical webinars, scientific topics, and research resources — free for registered HCPs.

Visit academy
Live
Academy Live

Live streaming of surgical procedures with moderated Q&A from operating surgeons.

See upcoming streams
Our portfolio is built for where you are.
Ready for where you're going.
academy.arclaser.com ↗
Next Steps

See why TruBlue remains the standard.

Option 01

Request a Demo

On-site demonstration with an A.R.C. clinical specialist. Evaluate TruBlue against your current platform.

Option 02

Schedule a Meeting

Connect with your local representative to discuss procedure fit, pricing, and regional availability.

Option 03

Download Evidence

PDF library of peer-reviewed publications with DOI links — read before you commit.

Get in Touch

A.R.C. clinical specialists coordinate demos with your team.

Manufacturer
A.R.C. Laser GmbH
Bessemerstraße 14
90411 Nürnberg, Germany
A.R.C. Laser GmbH · Nürnberg, Germany · 30+ years of laser engineering · ISO 13485 · FDA 510(k) · CE · UDI