Clinical Evidence

The most clinically established blue laser in ENT.

34 peer-reviewed publications — filter by specialty, each linked to its DOI. Click a card for the full abstract.

Publications: 34
Specialties: 5
Years: 2018–2024

Phonosurgery2024
Photoangiolysis with the 445-nm Blue Laser and the Potassium-Titanyl-Phosphate Laser: A Comparison
Cong-Kai Lin et al.
Objective: Photoangiolytic lasers have yielded significant innovation in laryngeal surgery in the last 25 years. After the discontinuation of the potassium titanyl phosphate (KTP) laser, a novel 445-nm blue laser was developed. The optimal…
Annals of Otology, Rhinology & Laryngo…
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Phonosurgery2023
Office-Based Laser Therapy for Vocal Fold Cyst: A Promising Alternative Therapy Using the 445 nm Blue Laser
Abdul-Latif Hamdan et al.
Vocal fold cysts are benign lesions commonly encountered in laryngology practice. They are traditionally classified as mucus retention cysts and epidermoid cysts. The mainstay treatment is surgical excision with diligent dissection of the c…
Journal of Voice (2023)
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Phonosurgery2023
Office-Based Treatment of Vocal Fold Polyps and Reinke's Edema: A Rational Comparison With Suspension Laryngoscopy
Marta Filauro et al.
Objective: Benign laryngeal lesions have traditionally been treated through suspension laryngoscopy under general anesthesia (GA). Recently, the development of operative videoendoscopes coupled with photoangiolytic lasers has allowed clinic…
The Laryngoscope, 00:1-8, 2023
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Phonosurgery2022
Unsedated Office-Based Blue Laser Therapy in Female Patients With Reinke's Edema: A Retrospective Review of 8 Cases
Anthony Ghanem et al.
Objectives: To report on the outcomes of unsedated blue laser therapy in female patients with Reinke's edema. Study design: Retrospective chart review. Methods: A retrospective chart review of female patients undergoing unsedated office-bas…
J Voice. 2022 Oct 8; S0892-1997(22)002…
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Phonosurgery2022
Surgical Outcome of Low-Power-Density Blue Laser for Vascular Lesions of the Vocal Fold
Bailey Balouch et al.
Summary: Photoangiolytic lasers such as the 532-nm potassium-titanyl-phosphate (KTP) and the novel 445-nm blue laser (introduced into the United States in 2020) are absorbed selectively by hemoglobin, permitting targeted ablation of vascula…
Journal of Voice
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Phonosurgery2022
Clinical aspects of laser surgery for chronic laryngeal diseases
A.A. Krivopalov et al.
Introduction: The problem of phonosurgery remains relevant today since the prevalence of benign and tumor-like laryngeal lesions is up to 55-70% among the productive pathology of the upper respiratory tract. A new 445 nm surgical laser havi…
Head and Neck Russian Journal Vol 10, …
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Phonosurgery2021
Endolaryngeal surgery of benign vocal fold lesions with a 445 nm semiconductor laser: postoperative management
Krivopalov A.A. et al.
Introduction: Today the high prevalence of benign vocal fold lesions is shown (up to 55-70%). The possibilities of surgical management of this pathology are very extensive. Laser technologies are becoming more and more popular among high-te…
Meditsinskiy sovet = Medical Council. …
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Phonosurgery2021
Un-sedated Office-Based Application of Blue Laser in Vocal Fold Lesions
Abdul Latif Hamdan et al.
Introduction: Office-based laser procedures in laryngology have gained a lot of popularity in the last decade with the use of the KTP, PDL and Thulium lasers. Preliminary investigations currently report on the use of the 445 nm wavelength B…
Journal of Voice (2021)
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Phonosurgery2021
Surgery of benign and tumor-like laryngeal formations using 445 nm semiconductor laser
Krivopalov A.A. et al.
The issues of phonosurgery remain truly relevant today since there is a high prevalence of benign and tumorlike laryngeal formations among the pathology of the upper respiratory tract (up to 55–70%). Nowadays, laser technologies are coming…
Rossiiskaya otorinolaringologiya. 2021…
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Phonosurgery2020
Blue Light Laser Results in Less Vocal Fold Scarring Compared to KTP Laser in Normal Rat Vocal Folds
R. Jun Lin et al.
Objectives: Preliminary investigations suggest that a novel blue light (BL) laser with a wavelength of 445 nm is comparable to the commonly utilized potassium titanyl phosphate (KTP) laser (532 nm) for treatment of various laryngeal patholo…
Laryngoscope. 2021 Apr;131(4):853-858
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Phonosurgery2020
Percutaneous fibre guided laser surgery of the endolarynx
Markus M Hess et al.
Occasionally, getting access to the larynx for an intervention can be challenging. Markus Hess and Susanne Fleischer describe a novel way to perform laser treatment in such difficult instances. Method and results: Our patient (male, aged 33…
ENT & Audiology News
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Phonosurgery2020
Angiolytic laser applications for the larynx; Phonosurgical concepts for transoral laser microsurgery
Sjeth S. et al.
Transoral laser microsurgery (TLM) for treatment of laryngeal cancer has reduced temporary tracheotomies, increased organ preservation rates, and improved functional results. Gold standard for laser-based transoral resection of laryngeal ca…
HNO. 2020 Jan; 68(1):59-68 (German)
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Photoangiolysis with the 445-nm Blue Laser and the Potassium-Titanyl-Phosphate Laser: A Comparison

Office-Based Laser Therapy for Vocal Fold Cyst: A Promising Alternative Therapy Using the 445 nm Blue Laser

Office-Based Treatment of Vocal Fold Polyps and Reinke's Edema: A Rational Comparison With Suspension Laryngoscopy

Unsedated Office-Based Blue Laser Therapy in Female Patients With Reinke's Edema: A Retrospective Review of 8 Cases

Surgical Outcome of Low-Power-Density Blue Laser for Vascular Lesions of the Vocal Fold

Clinical aspects of laser surgery for chronic laryngeal diseases

Endolaryngeal surgery of benign vocal fold lesions with a 445 nm semiconductor laser: postoperative management

Un-sedated Office-Based Application of Blue Laser in Vocal Fold Lesions

Surgery of benign and tumor-like laryngeal formations using 445 nm semiconductor laser

Blue Light Laser Results in Less Vocal Fold Scarring Compared to KTP Laser in Normal Rat Vocal Folds

Percutaneous fibre guided laser surgery of the endolarynx

Angiolytic laser applications for the larynx; Phonosurgical concepts for transoral laser microsurgery